Here is an interesting article by Massimo Pigliucci on several questions relating to the unification of knowledge. I find it sensible, though it’s written from a naturalistic perspective, so of course I would. The conclusion:
This isn’t a suggestion to give up, much less a mystical injunction to go ‘beyond science’. There is nothing beyond science. But there is important stuff before it: there are human emotions, expressed by literature, music and the visual arts; there is culture; there is history. The best understanding of the whole shebang that humanity can hope for will involve a continuous dialogue between all our various disciplines. This is a more humble take on human knowledge than the quest for consilience, but it is one that, ironically, is more in synch with what the natural sciences tell us about being human.